Revolutionary age control plant stem-cell technology
Using the
latest cutting-edge technology to protect the cells in the
skin, emerginC is proud to unveil its most recent
innovation, Protocell Cream and Protocell Eye –
scientifically proven, advanced skincare products that
provide serious anti-ageing results for all skin types, with
a focus on age-management.
The technology
behind Protocell Cream and Protocell eye
incorporates plant stem-cells that have been carefully
extracted from a rare type of organic Swiss apple.
These plant cells are rich in factors which are capable of
protecting and enhancing the longevity and vitality of skin
cells, therefore helping to recapture and preserve the skins
own natural youthfulness and radiance.
Protocell
Cream and
Protocell eye are also infused with the seeds, peel, and
oil from French cider apple harvested in Normandy and
Brittany. Studies reveal that extracts taken from these
particular apples are powerful anti-oxidants, protecting the
skin against environmental damage, and promoting firmer,
smoother, stronger skin.
Another potent
ingredient in Protocell is Aqua Cacteen, an
ultra refined elixir from the prickly pear Opuntia Cactus, a
cactus rich in flavones, vitamins, anti-oxidants, minerals
and polysaccharides, and known for its super-hydrating,
protecting, and soothing properties.
Protocell
also contains another robust ingredient, Argan Oil, a
very rare and precious oil that has been a coveted beauty
secret of Moroccan women for hundreds of years. Indigenous
to South Morocco, this precious oil is extracted from the
kernels of the Argan tree. Argan Oil has numerous benefits;
it helps preserve cell integrity, nourishes dry and
dehydrated skin, heals and regenerates damaged skin, helps
reduce the appearance of wrinkles and is capable of
regulating and balancing the production of excess oil in
oily skin.
Extensive
laboratory studies of the active ingredients in both
Protocell Cream and Protocell Eye show a
significant and visible decrease in the wrinkle depth of
crow’s feet for 100% of subjects tested.
Used daily,
Protocell Cream effectively works to rejuvenate all skin
types, especially mature skin, and leaves a noticeably
more youthful, vibrant skin.
Protocell eye is
a super-lightweight eye emulsion, formulated with the same
plant stem-cell technology, argan oil and cactus extract,
and works to combat the visible signs of aging specifically
around the delicate eye zone.
Introduction Protocell technology
Skin Stem Cells and Plant Stem Cells
What are
Stem Cells?
Stem cells
are blank “un programed” cells, or cells that have
yet to become specialised. They are in an early stage of
development and have the ability to become any type of cell
to form skin, bones, organs or other body parts. Stem
cells can either replicate themselves, making more stem
cells, or generate differentiated cells which are
responsible for specific functions.
Are there
different kinds of stems cells?
Yes. Stem
cells come in three forms: embryonic stem cells, embryonic
germ cells and adult stem cells. Embryonic stem cells come
from embryos, embryonic germ cells from testes, and adult
stem cells can come from bone marrow.
Embryonic stem
cells have the ability to become virtually any type of cell
within the body. Adult stem cells are more limited. They are
found in adult organs. They are still developing and they
have the potential to become any of the major specialized
cell types within that organ. But recent evidence suggests
it may be possible to reprogram adult stems to repair
tissue.
The Role of
Stem Cells in the Skin
Our skin
contains many types of stem cells. They provide a constant
source of new cells to maintain the skins functions and
youthfulness.
Because skin
cells in the epidermis are naturally shed from the skin,
there must be a continuous delivery of newly differentiating
cells illustrating the importance of Stem Cells in the skin.
The basal
layer of the epidermis contains two basic types of cells:-
1) The slowly
dividing epidermal stem cells (that represent about 2-7% of
the basal cell population) and
2) The cells
that they produce, that are rapidly diving cells that supply
new cells to replace those that are shed, lost or dying
through the skin’s natural desquamation process.
The process of
stem cell self-renewal is slow, as stem cells die after a
certain number of divisions and because each time the cells
divide there is a risk of DNA mutation. Senescence is the
natural process that, after approximately 50 divisions stops
the cells being able to undergo further divisions and a
major cause of tissue ageing. While a natural process,
Senescence can also occur “prematurely” e.g. as a result of
damage to the cellular DNA. This premature Senescence is
especially detrimental when it occurs in stem cells, because
they are essential for tissue regeneration.
So what can be done? Scientists turned to plants for the
answer.
Plant Stem
Cells and their effect on the skin
Plants also
have stem cells. Like humans, plant stem cells depend on
epigenetic control and signals from surrounding cells for
their development. Unlike humans, however, each
plant-derived adult stem cell possesses the ability to
generate a whole new plant. Plant tissue cultures can be
produced from nearly all plant tissues.
Through the
use of completely new, patent pending cell culture
technology, Swiss scientists at Mibelle Biochemistry have
been able to obtain stem cell components from within the
cells and grow plant stem cells from a rare and almost
extinct Swiss apple tree (var. Uttwiler Spatlauber).
This variety
of apple is renowned for its incredible storage properties
and ability to stay fresh for long periods of time. It must
therefore have very long-living tissue stem cells.
After years of
testing this extract, scientists confirmed that the
extracted components are rich in special factors that have a
positive effect on human stem cells and are capable of
protecting and maintaining the functions of skin stem cells.
In addition,
these important extracts also promote the longevity of these
essential skin stem sells, therefore ensuring skin
rejuvenation, youthful look, vitality of your skin and
delaying signs of premature skin ageing in ways never before
possible. Just a tiny amount applied to your face, neck, and
décolleté area, twice daily, can help revitalize the tone,
texture, and appearance of aging skin.
Results below
illustrate that PhytoCellTech Malus Domestica (the name
given to this rare Swiss apple extract) positively
influences resistance and is against senescence and, in
particular,
premature
senescence of human stem cells, therefore helping to
preserve and protect your vital skin stem cells.
Protocell
Clinical Studies
The
anti-wrinkle effect of PhytoCellTec Malus Domestica was
evaluated in a study with 20 volunteers aged from 37 to 64.
An emulsion of 2% of PhytoCellTec Malus Domestica was
applied twice daily for 28 days to the crow’s feet. Wrinkle
depth was determined by means of PRIMOS (phase-shifting
rapid in vivo measurement of skin). Results showed a
significant and visible decrease in wrinkle depth for 100%
of the subjects.
Before (Day
0)
After (Day 28)
*A
clinical study conducted by Val de Vire bioactives showed a
reduction of wrinkle depth with a formula containing 0.4% of
Pomactiv Hfv applied during 28 days (apple seed oil).
Results showed a 50% reduction of wrinkle depth at cross
foot level on Day 28.
Day
0
Day 14
Day 28
Study Results:
*Increase in skin firmness with 2% AquaCacteen, studied by
Mibelle AG Biochemistry
*Increase in skin hydration with a shower gel containing
AquaCacteen, studied by Mibelle AG Biochemistry
Val de
Vire (Cider Apple)
Pomactiv Hfv regulates the action of grow factors
(Cytokines) responsible for tissue repair and renewal.
Significant modifications of collagen genes expression.
Correct Collagen Formation: wrinkles reduction and dermal
repair of aged skin, improved skin elasticity and tonicity.
Anti-wrinkles evaluation:
study
made on 20 women aged (35 - 60 years)
Application during 4 weeks of an anti-age cream containing
0.4% pomactiv hfv
Results: evaluation of wrinkle depth at crow's foot level
measured by profile of lines on D0, D14, D28
-18% of
wrinkles depth on D14
-20% of
wrinkles depth on D28
Improvement of skin roughness (-8% D14, -16% D28)
Lipogenesis inhibition:
Control
- adipocytes cells on differentiated
Adipocytes differenciated without pomaeceo cqr - cellular
lipidis accumulation
Adipocytes differenciated with pomaceo cqr after 11 days of
culture - cellular lipidis decrease *
Anti-cellulite/firmness evaluation:
Study
made on 20 women having noticeable cellulite on thighs.
Application during 4 weeks of a slimming gel containing 0.4%
pomactiv hfv. Subjective results - noticeable improved skin
elasticity on D28, significant reduction of orange peel
effect D14 and 28, improved smooth skin aspect D28
PhytoCellTec Malus Domestica:
Maintenance of Stem Cell Growth
-
An
in-vitro test was conducted on umbilical cord blood stem
cells with Malus Domestica stem cell extract which is the
active component of PhytoCellTec Malus Domestica. Umbilical
cord blood stem cells (UCBSC) are the "youngest" safely
available stem cells for research. The influence of Malus
Domestica stem cell extract on UCBSC artificial growth was
evaluated by counting the cell number after incubation.
Results
showed that Malus Domestica stem cell extract has a positive
effect on UCBSC's artificial growth thus maintaining the
growth and proliferative activity of UCBSC.
Protection against UV Radiation
-
A
second in-vitro test was conducted on umbilical cord blood
stem cells with Malus Domestica stem cell extract which is
the active component of PhytoCellTec Malus Domestica. The
protective effect against UV damage of Malus Domestica stem
cell extract on UCBSC was evaluated by an MTS assay. UCBSC
were incubated with different concentrations of Malus
Domestica stem cell extract for 24 hr and then exposed to UV
radiation. The MTS assay, which measures the number of
living cells and therefore the damage from UV, was performed
48 hr after UV radiation.
Results
showed the capacity of Malus Domestica stem cell extract to
protect UCBSC from UV damage even at low concentrations.
Effect
on Gene Expression in Senescent Dermal Fibroblasts
-
Recently a cellular model for premature senescence was
established based on normal human dermal fibroblasts. After
2 hrs of treatment with H202, the cells showed typical signs
of senescence. This model was used to prove the
anti-senescence effect of Malus Domestica stem cell extract.
After the H202 treatment, the fibroblast cells were
incubated with a 2% extract for 144 hrs. Then gene
expression was analyzed with a DNA array system comprising
150 probes.
Results
showed that Malus Domestica stem cell extract can
up-regulate specific genes involved in delay of senescence,
protection against oxidative stress, and repair of DNA.
Testimonials From Our Clients
"I
just want to take the time to say
what fantastic and prompt service I
have received from you. I received
my parcel of Thalgo today express
post . Everything was great and so
quick. Thanks for keeping
me informed of what was happening
and I will be ordering from you
again. How easy you don't need to
move from your house and your parcel
gets delivered right to your door.
The free delivery sets you above the
rest. Well done". (Daniela,
Blawin, VIC)
"I
just wanted to say thank you for
sending the products, they arrived
yesterday safe and sound.
I'll be definitely ordering from
you from now on. My husband has
already asked me if I can order
Thalgo products for men. The
discounts offered are wonderful (I
saved over $30), and to receive the
products the next day without a
delivery fee is a fantastic service.
It's amazing, it's actually much
cheaper and easier for me to
purchase online from you, thousands
of kms away than to go to my usual
beauty therapist in Perth!
Thank you again." (Amanda, Perth
WA)
"The
order has arrived. Thank you
very much. Much faster then where I
normally purchase my skincare
online. Look forward to my next
order!" (Emma, Dysart, QLD).
Complete the Face Mapping Consult Card and either email to
northmeadbeauty@primusonline.com.au or fax; 02 9639 0982
and one of our skin care therapists will call you straight back to discuss your
individual requirements.
For further information about any of
the information above please contact
Northmead Beauty Therapy - 9890 7444 and speak to one of our
friendly therapists.
